Cristiano Ronaldo, Wayne Rooney, Chris Eagles, and Patrice Evra score a goal apiece for the Premier League champions.
Jim Ratcliffe pledged to invest $300 million in Manchester United to try to revive its fortunes.
James Milner sets a new Premier League record with his 654th appearance as Brighton beat Brentford 2-0, surpassing Gareth Barry's mark.
Observers say the transfer could be worth around 25 million pounds.
'Pure, unadulterated football joy has been in short supply for United fans for a long time now,' complains Dhruv Munjal.
City, Liverpool all cruise in respective FA Cup matches played on Saturday.
Jose Mourinho's side have been the most impressive of any of the title contenders.
Manchester United conceded two late own goals to allow Sevilla to snatch a 2-2 draw in the first leg of their Europa League quarter-final at Old Trafford on Thursday.
French midfielder Paul Pogba conceded the volume of different coaches he played under at Manchester United hindered his chances of success in England, while he also insisted he is pleased to be "home" at Juventus.
British media said Arsenal had allocated only 8,000 tickets for United supporters, citing safety concerns.
United sacked manager Jose Mourinho on Tuesday after the sixth-placed side made their worst start to a season for 28 years.
'When you are outside the top four I don't think you should speak about the title'
Manchester United's miserable season continued with a 3-2 home defeat by Galatasaray.
Manchester United kicked off their Europa League campaign poorly, losing 0-1 at home to Real Sociedad, while Arsenal's new signing Marquinhos scored in a 2-1 win at FC Zurich on Thursday.
On a good night for English clubs in the Europa League, Manchester United hammered AZ Alkmaar 4-0, while Wolverhampton Wanderers also thrashed Besiktas 4-0 in Group K, and Arsenal came from two goals down to draw 2-2 away to Standard Liege and finish first in their pool. The upset of the night came in Group J as Crivelli scored a 90th-minute winner against Borussia Moenchengladbach to send Basaksehir through and knock the Germans out, with AS Roma grabbing the runner-up spot thanks to a 2-2 home draw with Wolfsberger as the Europa League group stage concluded on Thursday.
Manchester United will be without Ryan Giggs, Gary Neville and Louis Saha for the Champions League Group F match against FC Copenhagen on Wednesday.
IMAGES from the Europa League matches played on Thursday.
Manchester United manager Jose Mourinho said Friday's draw for the last 16 of the Europa League against Russian side Rostov has been unkind to his team, the favourites.
The English Premier League champions demolished the Chinese Super League team in the third game of their Asian tour.
Manchester United will exercise their option to extend veteran striker Zlatan Ibrahimovic's contract for a second season at Old Trafford, manager Jose Mourinho said on Wednesday. The 35-year-old Ibrahimovic, who joined on a free transfer in July, has had a mixed start to his United career despite scoring eight goals in 17 games in all competitions. "Zlatan's situation is simple: he has a one-plus-one contract with the club and we will execute the option of a second season," Mourinho told reporters.
Manchester United captain Wayne Rooney has been left out of the 18-man squad travelling to face Danish side FC Midtjylland in the Europa League on Thursday, the Premier League club said on their website (www.manutd.com). With United fifth in the league table, six points off the top-four, the 30-year-old striker recently said that winning the Europa League or the FA Cup could save their disappointing season. Combative midfielder Marouane Fellaini was another notable absentee and full back Matteo Darmian will not be involved after dislocating his shoulder during Saturday's 2-1 league defeat by Sunderland.
Former Europa League winners Manchester United booked a quarter-final spot in the tournament after their second-string side laboured to a 2-1 home win over LASK Linz on Wednesday to seal a 7-1 aggregate rout of the Austrian side.
A round-up of Tuesday's action in the UEFA Champions League.
News of Van Gaal's impending departure from the club leaked out minutes after Saturday's 2-1 extra-time victory over Palace and, following relentless media speculation and a day of negotiations, it was confirmed by both sides on Monday evening.
In what could be a game-changing move for the struggling East Bengal, EPL giants Manchester United may end up taking the ownership of one of oldest football clubs in the country.
'Being back in the Champions League is going back to the natural habitat. Manchester United (have been there) season after season'
The move came after Manchester-born Rashford, who made 426 senior appearances and scored 138 goals for United in all competitions, fell out of favour with manager Ruben Amorim.
Barcelona were third on 648.3 million euros.
Raphinha excited to follow in footsteps of Brazilian greats at Barcelona
Manchester United defender Cameron Borthwick-Jackson has joined Wolves on a season-long loan, the Premier League club confirmed on Twitter.
Armenia midfielder Henrikh Mkhitaryan has joined Manchester United from Borussia Dortmund, the German club said on Saturday. The 27-year-old became the Premier League team's third high-profile signing since the appointment of Jose Mourinho as manager in May, following defender Eric Bailly and striker Zlatan Ibrahimovic to Old Trafford.
Kazakhstan's Astana fought back to beat a youthful Manchester United side 2-1 at home, Arsenal's woes continued as Frankfurt's Daichi Kamada scored twice to secure a 2-1 win.
'That was quite an empty period in this club with no evolution in areas that are important'
France international striker Antoine Griezmann has reached an agreement with Manchester United over a transfer from Atletico Madrid at the end of the season, Yahoo Sport has reported.
Responding to an initiative already run by fans of both clubs, City and United will donate 50,000 pounds each to the Trussell Trust, a support network of more than 1,200 food banks.
Manchester United must learn to ignore their critics as their performances may have been affected by the intense scrutiny the team have been under throughout the campaign, manager Louis van Gaal said on Wednesday.
Eriksen seeks return to 'normal life' with Brentford
Manchester United need to win trophy to save season, says Wayne Rooney.
Barcelona staged a thrilling second-half comeback to defeat Levante 3-2 away in LaLiga on Saturday, overcoming a two-goal deficit after a poor first-half display.
IMAGES from the English Premier League matches played on Tuesday